Related references
Note: Only part of the references are listed.Regression of metastatic melanoma in a patient by antibody targeting of cancer stem cells
Max Schlaak et al.
Oncotarget (2015)
Sox2 promotes tamoxifen resistance in breast cancer cells
Marco Piva et al.
EMBO MOLECULAR MEDICINE (2014)
Sox2 Requirement in Sonic Hedgehog-Associated Medulloblastoma
Julia Ahlfeld et al.
CANCER RESEARCH (2013)
SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma
Petra M. Bareiss et al.
CANCER RESEARCH (2013)
Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression
Sreelatha Gopinath et al.
CARCINOGENESIS (2013)
SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells
Adrian P. Rybak et al.
CELLULAR SIGNALLING (2013)
Diagnostic utility of neural stem and progenitor cell markers nestin and SOX2 in distinguishing nodal melanocytic nevi from metastatic melanomas
Pei-Ling Chen et al.
MODERN PATHOLOGY (2013)
WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function
S. Pandolfi et al.
ONCOGENE (2013)
NVP-LDE225, a potent and Selective SMOOTHENED Antagonist Reduces Melanoma Growth In Vitro and In Vivo
Ahmad Jalili et al.
PLOS ONE (2013)
The Emerging Role of SOX2 in Cell Proliferation and Survival and Its Crosstalk with Oncogenic Signaling in Lung Cancer
Yu-Ting Chou et al.
STEM CELLS (2013)
SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells
M. Herreros-Villanueva et al.
ONCOGENESIS (2013)
Hedgehog Pathway Blockade Inhibits Melanoma Cell Growth in Vitro and in Vivo
Kathryn E. O'Reilly et al.
PHARMACEUTICALS (2013)
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest
Igor Adameyko et al.
DEVELOPMENT (2012)
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells
Markus Eberl et al.
EMBO MOLECULAR MEDICINE (2012)
SOX2 contributes to melanoma cell invasion
Sasha D. Girouard et al.
LABORATORY INVESTIGATION (2012)
Targeting CD20 in Melanoma Patients at High Risk of Disease Recurrence
Alice Pinc et al.
MOLECULAR THERAPY (2012)
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
Charles M. Rudin et al.
NATURE GENETICS (2012)
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
Sabine Stolzenburg et al.
NUCLEIC ACIDS RESEARCH (2012)
Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
U. Basu-Roy et al.
ONCOGENE (2012)
Sox2 expression in breast tumours and activation in breast cancer stem cells
O. Leis et al.
ONCOGENE (2012)
Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation
S. M. Kumar et al.
ONCOGENE (2012)
Melanoma Chemotherapy Leads to the Selection of ABCB5-Expressing Cells
Marine Chartrain et al.
PLOS ONE (2012)
ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets
Yuchun Luo et al.
STEM CELLS (2012)
HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells
Roberta Santini et al.
STEM CELLS (2012)
Identification of a Polyoxometalate Inhibitor of the DNA Binding Activity of Sox2
Kamesh Narasimhan et al.
ACS CHEMICAL BIOLOGY (2011)
The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis
Xuefeng Fang et al.
BMC GENOMICS (2011)
Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth
Gianluca Civenni et al.
CANCER RESEARCH (2011)
Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice
Katrin Arnold et al.
CELL STEM CELL (2011)
Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
Isaac Brownell et al.
CELL STEM CELL (2011)
SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study
Alvaro C. Laga et al.
EXPERIMENTAL DERMATOLOGY (2011)
Melanoma stem cells: not rare, but well done
Sasha D. Girouard et al.
LABORATORY INVESTIGATION (2011)
SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity
Munehide Nakatsugawa et al.
LABORATORY INVESTIGATION (2011)
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
Erik Engelen et al.
NATURE GENETICS (2011)
Melanoma Spheroids Grown Under Neural Crest Cell Conditions Are Highly Plastic Migratory/Invasive Tumor Cells Endowed with Immunomodulator Function
Kiran Ramgolam et al.
PLOS ONE (2011)
Eradication of melanomas by targeted elimination of a minor subset of tumor cells
Patrick Schmidt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Expression of The Embryonic Stem Cell Transcription Factor SOX2 in Human Skin Relevance to Melanocyte and Merkel Cell Biology
Alvaro C. Laga et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
The transcription factor Sox2 is required for osteoblast self-renewal
U. Basu-Roy et al.
CELL DEATH AND DIFFERENTIATION (2010)
Hedgehog controls neural stem cells through p53-independent regulation of Nanog
Agnese Po et al.
EMBO JOURNAL (2010)
NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
Marie Zbinden et al.
EMBO JOURNAL (2010)
Recurrent Copy Number Gain of Transcription Factor SOX2 and Corresponding High Protein Expression in Oral Squamous Cell Carcinoma
Koija Freier et al.
GENES CHROMOSOMES & CANCER (2010)
Selection of Tumorigenic Melanoma Cells Using ALDH
Jim B. Boonyaratanakornkit et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)
Heterogeneous Phenotype of Human Melanoma Cells with In Vitro and In Vivo Features of Tumor-Initiating Cells
Michela Perego et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)
GLI2-Mediated Melanoma Invasion and Metastasis
Vasileia-Ismini Alexaki et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
Alexander D. Boiko et al.
NATURE (2010)
Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells
Chul-Ho Jeong et al.
STEM CELLS (2010)
A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
Barbara Stecca et al.
EMBO JOURNAL (2009)
Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
Jochen Utikal et al.
JOURNAL OF CELL SCIENCE (2009)
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
Yifang Hu et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
Adam J. Bass et al.
NATURE GENETICS (2009)
Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh
Rebecca Favaro et al.
NATURE NEUROSCIENCE (2009)
Gli2 Is a Novel Regulator of Sox2 Expression in Telencephalic Neuroepithelial Cells
Hiromi Takanaga et al.
STEM CELLS (2009)
Acetylation of Sox2 Induces Its Nuclear Export in Embryonic Stem Cells
Gretchen A. Baltus et al.
STEM CELLS (2009)
SOX2 Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity
Rosaria Maria Rita Gangemi et al.
STEM CELLS (2009)
Identification of cells initiating human melanomas
Tobias Schatton et al.
NATURE (2008)
Induced pluripotent stem cell lines derived from human somatic cells
Junying Yu et al.
SCIENCE (2007)
Sonic Hedgehog promotes the development of multipotent neural crest progenitors endowed with both mesenchymal and neural potentials
Giordano W. Calloni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
Shinji Masui et al.
NATURE CELL BIOLOGY (2007)
Melanomas require HEDGEHOG-GLI signaling reaulated by interactions between GLI1 and the RAS-MEK/AKT pathways
Barbara Stecca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential
Elena Monzani et al.
EUROPEAN JOURNAL OF CANCER (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon
S Miyagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A tumorigenic subpopulation with stem cell properties in melanomas
D Fang et al.
CANCER RESEARCH (2005)
ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma
NY Frank et al.
CANCER RESEARCH (2005)
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
K Hochedlinger et al.
CELL (2005)
Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle
ME Hutchin et al.
GENES & DEVELOPMENT (2005)
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
R Machold et al.
NEURON (2003)
SOX2 functions to maintain neural progenitor identity
V Graham et al.
NEURON (2003)
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
K Lai et al.
NATURE NEUROSCIENCE (2003)
Multipotent cell lineages in early mouse development depend on SOX2 function
AA Avilion et al.
GENES & DEVELOPMENT (2003)