Related references
Note: Only part of the references are listed.Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis
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BLOOD (2008)
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase
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Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication
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L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes
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Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC
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Cu14A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome
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MOLECULAR AND CELLULAR BIOLOGY (2006)
Involvement of CUL4 ubiquitin E3 ligases in regulating CDK inhibitors Dacapo/p27(Kip1) and cyclin E degradation
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CELL CYCLE (2006)
Centrosome amplification, chromosome instability and cancer development
K Fukasawa
CANCER LETTERS (2005)
Ddb1 controls genome stability and meiosis in fission yeast
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GENES & DEVELOPMENT (2005)
Ddb1 is required for the proteolysis of the Schizosaccharomyces pombe replication inhibitor Spd1 during S phase and after DNA damage
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase
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SCIENCE (2004)
Cul4A physically associates with MDM2 and participates in the proteolysis of p53
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CANCER RESEARCH (2004)
CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein
Y Zhang et al.
EMBO JOURNAL (2003)
Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint
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NATURE CELL BIOLOGY (2003)
Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components
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VIROLOGY (2002)
Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex
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JOURNAL OF VIROLOGY (2002)
CUL-4A is critical for early embryonic development
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MOLECULAR AND CELLULAR BIOLOGY (2002)
TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas
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HEPATOLOGY (2002)
The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cells
A Nag et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
p53-mediated DNA repair responses to UV radiation:: Studies of mouse cells lacking p53, p21, and/or gadd45 genes
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MOLECULAR AND CELLULAR BIOLOGY (2000)