4.3 Article

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Journal

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
Volume 16, Issue 5, Pages 284-287

Publisher

MARY ANN LIEBERT, INC
DOI: 10.1089/omi.2011.0118

Keywords

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Funding

  1. National 973 Projects of China [2011CB910700]
  2. Chang-Jiang Scholars Program
  3. 211 Projects
  4. National Natural Science Foundation of China [20871057]
  5. Guangdong Natural Science Research [32209003]
  6. Fundamental Research Funds for the Central Universities [21611303, 11610101]

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Increasing quantitative data generated from transcriptomics and proteomics require integrative strategies for analysis. Here, we present an R package, clusterProfiler that automates the process of biological-term classification and the enrichment analysis of gene clusters. The analysis module and visualization module were combined into a reusable workflow. Currently, clusterProfiler supports three species, including humans, mice, and yeast. Methods provided in this package can be easily extended to other species and ontologies. The clusterProfiler package is released under Artistic-2.0 License within Bioconductor project. The source code and vignette are freely available at http://bioconductor.org/packages/release/bioc/html/clusterProfiler.html

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