4.3 Article

The Impact and Management of Fibroids for Fertility An Evidence-Based Approach

Journal

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ogc.2012.09.005

Keywords

Leiomyoma; Infertility; Assisted reproductive technology (ART); Myomectomy; Hysteroscopy; Minimally invasive gynecologic surgeries; Magnetic resonance-guided focused ultrasound (MRgFUS); Uterine artery embolization (UAE)

Funding

  1. Intramural Research Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health
  2. National Institutes of Health
  3. NICHD
  4. PRAE
  5. IRTA program

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Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.

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