Journal
OBSTETRICS AND GYNECOLOGY
Volume 124, Issue 1, Pages 120-133Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/AOG.0000000000000346
Keywords
-
Categories
Funding
- Wellbeing of Women [RG1235] Funding Source: researchfish
Ask authors/readers for more resources
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of adverse perinatal outcomes, including spontaneous preterm delivery, meconium staining of the amniotic fluid, and stillbirth. It is commonly treated with ursodeoxycholic acid. There is accumulating evidence to suggest that intrahepatic cholestasis of pregnancy has a lasting influence on both maternal and fetal health. We review the etiology, diagnosis, and management of this intriguing condition.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available