Journal
OBSTETRICAL & GYNECOLOGICAL SURVEY
Volume 69, Issue 10, Pages 603-612Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/OGX.0000000000000111
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Puberty is a defining time of many adolescents' lives. It is a series of events that includes thelarche, pubarche, and menarche. Primary amenorrhea is the absence of menarche. There are numerous etiologies including outflow tract obstructions, gonadal dysgenesis, and anomalies of the hypothalamic axis. This review's aims are to define primary amenorrhea and describe the various causes, their workups, associated comorbidities, and treatment options. At the end, a generalist should be able to perform an assessment of an adolescent who presents with primary amenorrhea and, if warranted, begin initial treatment. Target Audience Obstetricians and gynecologists, family physicians Learning Objectives After completing this CME activity, physicians should be better able to perform and assess the findings of an initial workup on a patient with primary amenorrhea, identify the appropriate referral providers, and provide appropriate basic treatment for patients with primary amenorrhea.
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