Journal
OBESITY REVIEWS
Volume 15, Issue 10, Pages 781-790Publisher
WILEY
DOI: 10.1111/obr.12198
Keywords
Epidemiology; obesity phenotype; prevalence
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Funding
- Sao Paulo State Research Foundation-FAPESP [2012/05723-8]
- Brazilian Ministry of Education [CAPES BEX 13827/12-0]
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We performed a systematic review of the prevalence of metabolically healthy obesity (MHO). Medline, Web of Science and EMBASE were searched for original articles from inception to November 2013. Only prospective and cross-sectional studies were included. After screening 478 titles, we selected 55 publications, of which 27 were population-based studies and were used in the narrative synthesis. From the 27 studies, we identified 30 definitions of metabolic health, mainly based on four criteria: blood pressure, high-density lipoprotein cholesterol, triglycerides and plasma glucose. Body mass index 30kgm(-2) was the main indicator used to define obesity (74% of the studies). Overall, MHO prevalence ranged between 6% and 75%. In the studies that stratified the analysis by sex, prevalence was higher in women (seven out of nine studies) and in younger ages (all four studies). One-third of the studies (n=9) reported the response rate. Of these, four reported a response rate of 70% and they showed MHO prevalence estimates between 10% and 51%. The heterogeneity of MHO prevalence estimates described in this paper strengthens calls for the urgent need for a commonly established metabolic health definition.
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