Journal
NUTRITION REVIEWS
Volume 69, Issue -, Pages S17-S22Publisher
OXFORD UNIV PRESS INC
DOI: 10.1111/j.1753-4887.2011.00428.x
Keywords
anemia; iron deficiency; iron metabolism; placenta; pregnancy
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Funding
- Scottish Government
- European Union
- International Copper Association
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During pregnancy, the developing fetus is entirely dependent on its mother for nutrition and waste disposal, which take place almost exclusively across the placenta. The placenta is, however, not just a passive mediator; it can also regulate the rates and amounts of nutrient transported. This is particularly true for iron transport. This review examines how the fetus, and not the mother, regulates iron uptake and transfer across the placenta, how these processes interact, and how the fetus can modulate iron metabolism in the mother. (C) 2011 International Life Sciences Institute
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