Journal
NUTRITION REVIEWS
Volume 66, Issue 9, Pages 506-516Publisher
OXFORD UNIV PRESS INC
DOI: 10.1111/j.1753-4887.2008.00083.x
Keywords
androgen; dietary fiber; sex hormone-binding globulin; weight loss
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This review summarizes studies on the effect of various diets on circulating androgen levels and sex hormone-binding globulin (SHBG). Reduced caloric intake leading to significant weight loss increases SHBG levels regardless of diet composition, particularly in women. Cross-sectional studies show that dietary composition is generally not associated with SHBG levels independent of obesity level. No clear conclusion can be reached regarding the effect of various eating habits or dietary composition on circulating androgens. The evidence indicates that dietary effects on circulating SHBG, and possibly androgens, can be expected if bodyweight or fatness and/or insulin homeostasis are modulated. (C) 2008 International Life Sciences Institute.
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