Journal
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
Volume 22, Issue 4, Pages 307-311Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.numecd.2012.01.005
Keywords
Obesity; Type 2 diabetes; Cardiovascular; Mortality; Trends; Western countries
Funding
- ESRC [ES/J010014/1, ES/F029721/1] Funding Source: UKRI
- MRC [G0900847] Funding Source: UKRI
- Economic and Social Research Council [ES/J010014/1, ES/F029721/1] Funding Source: researchfish
- Medical Research Council [G0900847] Funding Source: researchfish
- Medical Research Council [G0900847] Funding Source: Medline
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The majority of Western countries have reported large falls in cardiovascular diseases (CVD) mortality rates since the 1970s. Yet since the 1980s, they have also experienced two-fold or three-fold increases in the prevalence of obesity and type 2 diabetes - both considered substantial risk factors for CVD. So why have these increasing risks apparently not impacted on CVD mortality falls? This viewpoint outlines the main factors involved; examines recent trends and apparent contradictions; offers some explanations for the trends; discusses how more usefully complex epidemiological models might lead to clearer evidence; offers some explanations for the trends; and explores the implications for CVD prevention. (c) 2012 Elsevier B.V. All rights reserved.
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