Journal
SYSTEMATIC AND APPLIED MICROBIOLOGY
Volume 38, Issue 4, Pages 258-265Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.syapm.2015.02.008
Keywords
Cultivation; Culture collections; Microbial resources; Preservation; Microbial diversity; Bioeconomy
Categories
Funding
- German Federal Ministry of Science and Education through the German Center of Infection Research (DZIF) [8000-105-3]
- German Federal Ministry of Science and Education through project 'The Future Okavangoi [01LL0912M]
- European Commission through funding of the preparatory phase of the Microbial Resource Research Infrastructure (MIRRI) [312251]
- German Federal Ministry of Science and Education through the FP7-project 'Marine Microorganisms: Cultivation Methods for Improving their Biotechnological Applicationsi (MaCuMBA) [311975]
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Isolated strains constitute the basis for microbial systematics as well as for numerous applications in biotechnology, pharmacology, agronomy and public health. Microbial resource centers (mBRCs) are institutions capable of safeguarding, maintaining and distributing authenticated microbial strains, their genomic DNA and the associated data in a quality-controlled manner. They allow the deposit and distribution of type strains that form the basis of microbial taxonomy. Beyond taxonomy, deposited strains enable follow-up scientific studies and lead to a significantly improved recognition of scientific work. Considerable added value is generated through the labor-intensive steps of enrichment, enrichment screening, isolation, characterization, conservation and long-term storage of microbial strains. Here, a microbial strain is calculated to attain a value of 9836 Euro through its isolation and another 918 Euro through its deposit, adding up to a total value of 10,754 Euro. mBRCs provide a highly cost-effective way of preserving this value of microbial strains. A considerable future challenge of mBRCs will be to secure a larger fraction of strains that are isolated in research labs worldwide. mBRCs provide the expert knowledge and the cultivation and preservation skills crucial to access the large fraction of uncharted microbial diversity. mBRCs also provide the expertise and support the depositors of microbial resources to meet new legal challenges after implementation of the Nagoya Protocol. A suitable roadmap is described that allows mBRCs to meet the new demands emerging in science, technology and economy through an integration of novel technology, expansion of their duties and establishing an improved global mBRC network. (C) 2015 Elsevier GmbH. All rights reserved.
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