Journal
NUTRITION
Volume 25, Issue 11-12, Pages 1206-1211Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nut.2009.06.014
Keywords
Biomarker; Bioactive constituents; Nutraceuticals; Health effect; Xenobiotics; Bioavailability; Intake; Phytochemicals
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The efficacy and safety of bioactive compounds depend on a few known and unknown parameters. What is a physiologic dose and how can that dose be defined in cases of bioactive compounds with a poor knowledge of supply and distribution? What safety sets are needed? How can individual aspects such as polymorphisms or differences in absorption be considered? A group of experts tried to answer these and related questions during the 23rd Hohenheim Consensus Meeting at the University of Hohenheim in Stuttgart. (C) 2009 Elsevier Inc. All rights reserved.
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