4.5 Article

Catalyst- and Solvent-Free Rapid Addition of Secondary Phosphine Chalcogenides to Aldehydes: Another Click Chemistry

Journal

SYNTHESIS-STUTTGART
Volume 47, Issue 11, Pages 1611-1622

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1380408

Keywords

addition; aldehydes; green method; phosphine chalcogenides

Funding

  1. Council on Grants of the President of the Russian Federation for State Support of Leading Scientific Schools [NSh-156.2014.3]

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An efficient catalyst- and solvent-free method for the synthesis of tertiary alpha-hydroxyphosphine chalcogenides, via the almost quantitative addition of secondary phosphine chalcogenides to diverse aldehydes under mild conditions (20-52 degrees C, from 10 min to 5 h), is reported.

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