Ruthenium(II) Tetradentate Schiff Base Complexes: Synthesis, Characterization, DNA Binding, and Antioxidant Studies

Four ruthenium(II) complexes of the type [Ru(CO)(EPh3)L] (where E= P/As; L= dibasic tetradentate Schiff base ligand) have been synthesized. Structural features were determined by various physicochemical and spectral techniques. The interactions of these compounds with CT-DNA were carried out by absorption spectroscopy, which indicated that the ligands and ruthenium(II) complexes bind to DNA via intercalation. Investigation of antioxidative property showed that all the ruthenium(II) complexes have significant radical scavenging potencies against DPPH radicals than ligands.