Journal
NUCLEIC ACIDS RESEARCH
Volume 43, Issue D1, Pages D82-D86Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gku1163
Keywords
-
Categories
Funding
- CREST research project of the Japan Science and Technology Corporation [11102558]
- Ministry of Education, Culture, Sports, Science and Technology [24114005, 22136005, 24570176]
- Publication of Scientific Research Results [228063]
- Grants-in-Aid for Scientific Research [24570176, 24114001, 24114005, 22136005] Funding Source: KAKEN
Ask authors/readers for more resources
The COXPRESdb (http://coxpresdb.jp) provides gene coexpression relationships for animal species. Here, we report the updates of the database, mainly focusing on the following two points. For the first point, we added RNAseq-based gene coexpression data for three species (human, mouse and fly), and largely increased the number of microarray experiments to nine species. The increase of the number of expression data with multiple platforms could enhance the reliability of coexpression data. For the second point, we refined the data assessment procedures, for each coexpressed gene list and for the total performance of a platform. The assessment of coexpressed gene list now uses more reasonable P-values derived from platform-specific null distribution. These developments greatly reduced pseudopredictions for directly associated genes, thus expanding the reliability of coexpression data to design new experiments and to discuss experimental results.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available