4.4 Article

Metal-Free N-Arylation of Indolines with Diaryliodonium Salts

Journal

SYNLETT
Volume 26, Issue 5, Pages 651-655

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1379885

Keywords

amination; hypervalent iodine; metal-free; arylation; indoline

Funding

  1. Deutsche Forschungsgemeinschaft (DFG)
  2. Fonds der Chemischen Industrie (Sachkostenzuschuss)
  3. Merck KGaA

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The N-arylation of indolines using diaryliodonium salts as electrophilic arylating reagents is described. Without the use of any additional additives, the desired N-aryl indolines could be obtained in up to 85% yield.

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