4.8 Article

CopraRNA and IntaRNA: predicting small RNA targets, networks and interaction domains

Journal

NUCLEIC ACIDS RESEARCH
Volume 42, Issue W1, Pages W119-W123

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gku359

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Funding

  1. Deutsche Forschungsgemeinschaft Focus Program Sensory and Regulatory RNAs in Prokaryotes [SPP1258]
  2. Bundesministerium fuer Bildung und Forschung (BMBF) [0316165]
  3. Excellence Initiative of the German Federal and State Governments [EXC 294]

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CopraRNA (Comparative prediction algorithm for small RNA targets) is the most recent asset to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the existing tool IntaRNA (Interacting RNAs) in order to predict targets, interaction domains and consequently the regulatory networks of bacterial small RNA molecules. The CopraRNA prediction results are accompanied by extensive postprocessing methods such as functional enrichment analysis and visualization of interacting regions. Here, we introduce the functionality of the CopraRNA and IntaRNA webservers and give detailed explanations on their postprocessing functionalities.

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