4.8 Article

Database resources of the National Center for Biotechnology Information

Journal

NUCLEIC ACIDS RESEARCH
Volume 43, Issue D1, Pages D6-D17

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gku1130

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Funding

  1. National Institutes of Health, National Library of Medicine

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The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank (R) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (Bookshelf, PubMed Central (PMC) and PubReader); medical genetics (ClinVar, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen); genes and genomics (BioProject, BioSample, dbSNP, dbVar, Epigenomics, Gene, Gene Expression Omnibus (GEO), Genome, HomoloGene, the Map Viewer, Nucleotide, PopSet, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser, Trace Archive and UniGene); and proteins and chemicals (Biosystems, COBALT, the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB), Protein Clusters, Protein and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for many of these databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets.

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