4.4 Article

Microwave-Assisted Catalyst-Free Synthesis of Substituted 1,2,4-Triazoles

Journal

SYNLETT
Volume 26, Issue 3, Pages 404-407

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1379734

Keywords

microwave; microwave-assisted organic synthesis; 1,2,4-triazoles; aryl hydrazine; formamide

Funding

  1. DST-FIST [CSI-174/2008]
  2. Natural Sciences and Engineering Research Council of Canada (NSERC)
  3. CSIR, New Delhi

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A simple, efficient, and mild method has been developed for the synthesis of substituted 1,2,4-triazoles from hydrazines and formamide under microwave irradiation. The reaction proceeds smoothly in the absence of a catalyst and shows excellent functional-group tolerance.

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