Journal
NUCLEIC ACIDS RESEARCH
Volume 43, Issue D1, Pages D240-D249Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gku1158
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Funding
- Service and Infrastructure, Swiss Institute of Bioinformatics
- UK Biotechnology and Biological Sciences Research Council [BB/L018241/1]
- UCL Impact Award, University College London
- Bayer CropScience NV
- Biomedical Vacation Studentship, Wellcome Trust Foundation
- BBSRC via the University College London Library
- EMBL
- Biotechnology and Biological Sciences Research Council [BB/L018241/1] Funding Source: researchfish
- BBSRC [BB/L018241/1] Funding Source: UKRI
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The Orthologous Matrix (OMA) project is a method and associated database inferring evolutionary relationships amongst currently 1706 complete proteomes (i.e. the protein sequence associated for every protein-coding gene in all genomes). In this update article, we present six major new developments in OMA: (i) a new web interface; (ii) Gene Ontology function predictions as part of the OMA pipeline; (iii) better support for plant genomes and in particular homeologs in the wheat genome; (iv) a new synteny viewer providing the genomic context of orthologs; (v) statically computed hierarchical orthologous groups subsets downloadable in OrthoXML format; and (vi) possibility to export parts of the all-against-all computations and to combine them with custom data for 'client-side' orthology prediction. OMA can be accessed through the OMA Browser and various programmatic interfaces at http://omabrowser.org.
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