Related references
Note: Only part of the references are listed.Synthetic Zinc Finger Proteins: The Advent of Targeted Gene Regulation and Genonne Modification Technologies
Charles A. Gersbach et al.
ACCOUNTS OF CHEMICAL RESEARCH (2014)
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells
Nicola A. Kearns et al.
DEVELOPMENT (2014)
Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine
Charles A. Gersbach et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2014)
Self- processing of ribozyme- flanked RNAs into guide RNAs in vitro and in vivo for CRISPR- mediated genome editing
Yangbin Gao et al.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY (2014)
Multiplexed and Programmable Regulation of Gene Networks with an Integrated RNA and CRISPR/Cas Toolkit in Human Cells
Lior Nissim et al.
MOLECULAR CELL (2014)
Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
Hiroko Koike-Yusa et al.
NATURE BIOTECHNOLOGY (2014)
Dimeric CRISPR RNA-guided Fokl nucleases for highly specific genome editing
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2014)
CRISPR-Cas systems for editing, regulating and targeting genomes
Jeffry D. Sander et al.
NATURE BIOTECHNOLOGY (2014)
Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing
Dirk Heck et al.
NATURE BIOTECHNOLOGY (2014)
Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression
Ami M. Kabadi et al.
METHODS (2014)
Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
Pablo Tebas et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
Ines Fonfara et al.
NUCLEIC ACIDS RESEARCH (2014)
High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs
Katarzyna Duda et al.
NUCLEIC ACIDS RESEARCH (2014)
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Ophir Shalem et al.
SCIENCE (2014)
Genetic Screens in Human Cells Using the CRISPR-Cas9 System
Tim Wang et al.
SCIENCE (2014)
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
Albert W. Cheng et al.
CELL RESEARCH (2013)
Targeted Methylation and Gene Silencing of VEGF-A in Human Cells by Using a Designed Dnmt3a-Dnmt3L Single-Chain Fusion Protein with Increased DNA Methylation Activity
Abu Nasar Siddique et al.
JOURNAL OF MOLECULAR BIOLOGY (2013)
Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients
David G. Ousterout et al.
MOLECULAR THERAPY (2013)
TALEN-based Gene Correction for Epidermolysis Bullosa
Mark J. Osborn et al.
MOLECULAR THERAPY (2013)
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins
Morgan L. Maeder et al.
NATURE BIOTECHNOLOGY (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
Locus-specific editing of histone modifications at endogenous enhancers
Eric M. Mendenhall et al.
NATURE BIOTECHNOLOGY (2013)
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
Seung Woo Cho et al.
NATURE BIOTECHNOLOGY (2013)
Efficient genome editing in zebrafish using a CRISPR-Cas system
Woong Y. Hwang et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
Pablo Perez-Pinera et al.
NATURE METHODS (2013)
Robust, synergistic regulation of human gene expression using TALE activators
Morgan L. Maeder et al.
NATURE METHODS (2013)
CRISPR RNA-guided activation of endogenous human genes
Morgan L. Maeder et al.
NATURE METHODS (2013)
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
Kevin M. Esvelt et al.
NATURE METHODS (2013)
Synergistic and tunable human gene activation by combinations of synthetic transcription factors
Pablo Perez-Pinera et al.
NATURE METHODS (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
Thomas Gaj et al.
TRENDS IN BIOTECHNOLOGY (2013)
Tunable and Multifunctional Eukaryotic Transcription Factors Based on CRISPR/Cas
Fahim Farzadfard et al.
ACS SYNTHETIC BIOLOGY (2013)
Advances in targeted genome editing
Pablo Perez-Pinera et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2012)
Light-Inducible Spatiotemporal Control of Gene Activation by Customizable Zinc Finger Transcription Factors
Lauren R. Polstein et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases
Pablo Perez-Pinera et al.
NUCLEIC ACIDS RESEARCH (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
Jizhong Zou et al.
BLOOD (2011)
In vivo genome editing restores haemostasis in a mouse model of haemophilia
Hojun Li et al.
NATURE (2011)
In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases
Vittorio Sebastiano et al.
STEM CELLS (2011)
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome
Russell C. DeKelver et al.
GENOME RESEARCH (2010)
Lentiviral Vector Gene Therapy: Effective and Safe?
Derek A. Persons
MOLECULAR THERAPY (2010)
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
Dirk Hockemeyer et al.
NATURE BIOTECHNOLOGY (2009)
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
Elena E. Perez et al.
NATURE BIOTECHNOLOGY (2008)
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
Angelo Lombardo et al.
NATURE BIOTECHNOLOGY (2007)
A novel approach for the construction of multiple shRNA expression vectors
Deming Gou et al.
JOURNAL OF GENE MEDICINE (2007)
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
FD Urnov et al.
NATURE (2005)
An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene
E Myslinski et al.
NUCLEIC ACIDS RESEARCH (2001)
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions - Activation of vascular endothelial growth factor A
PQ Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Synthetic zinc finger transcription factor action at an endogenous chromosomal site - Activation of the human erythropoietin gene
L Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Chemically regulated zinc finger transcription factors
RR Beerli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)