4.8 Article

lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs

Journal

NUCLEIC ACIDS RESEARCH
Volume 43, Issue D1, Pages D168-D173

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gku988

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Funding

  1. NHMRC Project Grant [APP1043971]
  2. CINSW Early Career Fellowship
  3. NHMRC Early Career Fellowship

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Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that have been described independently in the scientific literature. In addition to capturing a great proportion of the recent literature describing functions for individual lncRNAs, lncRNAdb now offers an improved user interface enabling greater accessibility to sequence information, expression data and the literature. The new features in lncRNAdb include the integration of Illumina Body Atlas expression profiles, nucleotide sequence information, a BLAST search tool and easy export of content via direct download or a REST API. lncRNAdb is now endorsed by RNAcentral and is in compliance with the International Nucleotide Sequence Database Collaboration.

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