4.8 Article

SAbDab: the structural antibody database

Journal

NUCLEIC ACIDS RESEARCH
Volume 42, Issue D1, Pages D1140-D1146

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkt1043

Keywords

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Funding

  1. Engineering and Physical Sciences Research Council (EPSRC)
  2. UCB Pharma
  3. Roche GmbH
  4. EPSRC
  5. EPSRC [EP/K032402/1] Funding Source: UKRI
  6. Engineering and Physical Sciences Research Council [1231608, EP/K032402/1] Funding Source: researchfish

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Structural antibody database (SAbDab; http://opig.stats.ox.ac.uk/webapps/sabdab) is an online resource containing all the publicly available antibody structures annotated and presented in a consistent fashion. The data are annotated with several properties including experimental information, gene details, correct heavy and light chain pairings, antigen details and, where available, antibody-antigen binding affinity. The user can select structures, according to these attributes as well as structural properties such as complementarity determining region loop conformation and variable domain orientation. Individual structures, datasets and the complete database can be downloaded.

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