Journal
NUCLEIC ACIDS RESEARCH
Volume 42, Issue D1, Pages D472-D477Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkt1102
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Funding
- National Human Genome Research Institute at the National Institutes of Health [U41 HG003751]
- Ontario Research (GL2) fund
- European Bioinformatics Institute
- European Commission (PSIMEx)
- Google Summer of Code Program
- National Institutes of Health [U41 HG003751]
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Reactome (http://www.reactome.org) is a manually curated open-source open-data resource of human pathways and reactions. The current version 46 describes 7088 human proteins (34% of the predicted human proteome), participating in 6744 reactions based on data extracted from 15 107 research publications with PubMed links. The Reactome Web site and analysis tool set have been completely redesigned to increase speed, flexibility and user friendliness. The data model has been extended to support annotation of disease processes due to infectious agents and to mutation.
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