Related references
Note: Only part of the references are listed.FEN Nucleases: Bind, Bend, Fray, Cut
R. Scott Williams et al.
CELL (2011)
Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily
Susan E. Tsutakawa et al.
CELL (2011)
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
Jillian Orans et al.
CELL (2011)
Neutralizing Mutations of Carboxylates That Bind Metal 2 in T5 Flap Endonuclease Result in an Enzyme That Still Requires Two Metal Ions
Christopher G. Tomlinson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay
Martin Jinek et al.
MOLECULAR CELL (2011)
Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1
Jeong Ho Chang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Functional regulation of FEN1 nuclease and its link to cancer
Li Zheng et al.
NUCLEIC ACIDS RESEARCH (2011)
Substrate recognition and catalysis by flap endonucleases and related enzymes
Christopher G. Tomlinson et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2010)
Bronsted Analysis and Rate-Limiting Steps for the T5 Flap Endonuclease Catalyzed Hydrolysis of Exonucleolytic Substrates
Blanka Sengerova et al.
BIOCHEMISTRY (2010)
Flap Endonuclease 1 Mechanism Analysis Indicates Flap Base Binding Prior to Threading
Jason W. Gloor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding
Zhigang Guo et al.
NATURE CHEMICAL BIOLOGY (2010)
A streptavidin variant with slower biotin dissociation and increased mechanostability
Claire E. Chivers et al.
NATURE METHODS (2010)
Coordination of dual incision and repair synthesis in human nucleotide excision repair
Lidija Staresincic et al.
EMBO JOURNAL (2009)
The 3′-Flap Pocket of Human Flap Endonuclease 1 Is Critical for Substrate Binding and Catalysis
L. David Finger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structure and function of the 5′→3′ exoribonuclease Rat1 and its activating partner Rai1
Song Xiang et al.
NATURE (2009)
Rapid and efficient DNA strand cross-linking by click chemistry
Petr Kocalka et al.
CHEMBIOCHEM (2008)
Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease
Cynthia T. McMurray
DNA REPAIR (2008)
Three metal ions participate in the reaction catalyzed by T5 flap endonuclease
Karl Syson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Identification of Holliday junction resolvases from humans and yeast
Stephen C. Y. Ip et al.
NATURE (2008)
Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substrates
Juliette M. Devos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease
Ryan Williams et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
The intricate structural chemistry of base excision repair machinery: Implications for DNA damage recognition, removal, and repair
Kenichi Hitomi et al.
DNA REPAIR (2007)
Novel synthesis of O-6-alkylguanine containing oligodeoxyribonucleotides as substrates for the human DNA repair protein, O-6-methylguanine DNA methyltransferase (MGMT)
T Shibata et al.
NUCLEIC ACIDS RESEARCH (2006)
Structural basis for recruitment of human flap endonuclease 1 to PCNA
S Sakurai et al.
EMBO JOURNAL (2005)
The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors
LN Tumey et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
The Fen1 extrahelical 3′-flap pocket is conserved from archaea to human and regulates DNA substrate specificity
E Friedrich-Heineken et al.
NUCLEIC ACIDS RESEARCH (2004)
Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair
BR Chapados et al.
CELL (2004)
Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
E Larsen et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG
M Hohl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease
MR Tock et al.
EMBO JOURNAL (2003)
The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair
F Storici et al.
EMBO JOURNAL (2002)
A conserved tyrosine residue aids ternary complex formation, but not catalysis, in phage T5 flap endonuclease
D Patel et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2
Y Matsuzaki et al.
NUCLEIC ACIDS RESEARCH (2002)
Contacts between the 5′ nuclease of DNA polymerase I and its DNA substrate
Y Xu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)