4.8 Article

Target mRNA inhibition by oligonucleotide drugs in man

Related references

Note: Only part of the references are listed.
Review Allergy

Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor

N. A. Molfino et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2012)

Editorial Material Pharmacology & Pharmacy

Obatoclax mesylate: pharmacology and potential for therapy of hematological neoplasms

Jamal Joudeh et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2012)

News Item Biochemistry & Molecular Biology

Cancer drug's survivin suppression called into question

David Holmes

NATURE MEDICINE (2012)

Editorial Material Biotechnology & Applied Microbiology

Outlook for the next 5 years in drug innovation

Roy Berggren et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Article Oncology

Survivin in Solid Tumors: Rationale for Development of Inhibitors

David N. Church et al.

CURRENT ONCOLOGY REPORTS (2012)

Article Critical Care Medicine

RNA Interference Therapy in Lung Transplant Patients Infected with Respiratory Syncytial Virus

Martin R. Zamora et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Allergy

TPI ASM8 reduces eosinophil progenitors in sputum after allergen challenge

H. Imaoka et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2011)

Editorial Material Oncology

Therapeutic Oligonucleotides: The Road Not Taken

Cy A. Stein et al.

CLINICAL CANCER RESEARCH (2011)

Review Biochemistry & Molecular Biology

Therapeutic potential of antisense oligonucleotides for the management of dyslipidemia

Rosanne M. Crooke et al.

CLINICAL LIPIDOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Efficacy of apolipoprotein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia

Fatima Akdim et al.

EUROPEAN HEART JOURNAL (2011)

Review Pharmacology & Pharmacy

Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis

Xin Ming

EXPERT OPINION ON DRUG DELIVERY (2011)

Review Biochemistry & Molecular Biology

Pharmacokinetic evaluation of oblimersen sodium for the treatment of chronic lymphocytic leukemia

Pooja P. Advani et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2011)

News Item Biotechnology & Applied Microbiology

The long march of antisense

Dan Jones

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Biotechnology & Applied Microbiology

How were new medicines discovered?

David C. Swinney et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Review Biotechnology & Applied Microbiology

Targeting RNA to treat neuromuscular disease

Francesco Muntoni et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Medicine, General & Internal

Systemic Administration of PRO051 in Duchenne's Muscular Dystrophy

Nathalie M. Goemans et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Review Pharmacology & Pharmacy

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

C. Frank Bennett et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)

Article Oncology

Targeting the Cytoprotective Chaperone, Clusterin, for Treatment of Advanced Cancer

Amina Zoubeidi et al.

CLINICAL CANCER RESEARCH (2010)

Review Biochemistry & Molecular Biology

Apolipoprotein B synthesis inhibition: results from clinical trials

Maartje E. Visser et al.

CURRENT OPINION IN LIPIDOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy

Fatima Akdim et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

Article Multidisciplinary Sciences

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

John DeVincenzo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Oncology

Phase II Trial of OGX-011 in Combination with Docetaxel in Metastatic Breast Cancer

Stephen Chia et al.

CLINICAL CANCER RESEARCH (2009)

Review Oncology

Treatment of malignant gliomas with TGF-β2 antisense oligonucleotides

Peter Hau et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2009)

Article Critical Care Medicine

Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses

Gail M. Gauvreau et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)

Article Biotechnology & Applied Microbiology

Antisense inhibition of ICAM-1 expression as therapy provides insight into basic inflammatory pathways through early experiences in IBD

Jessica R. Philpott et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2008)

Article Oncology

A Phase I/II study of GTI-2040 and capecitabine in patients with renal cell carcinoma

Walter M. Stadler et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)

Review Biochemistry & Molecular Biology

Genomics: success or failure to deliver drug targets?

UAK Betz et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2005)

Review Biochemistry & Molecular Biology

Overview of ribonucleotide reductase inhibitors: An appealing target in anti-tumour therapy

NMFSA Cerqueira et al.

CURRENT MEDICINAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

eIF-4E expression and its role in malignancies and metastases

A De Benedetti et al.

ONCOGENE (2004)

Article Biotechnology & Applied Microbiology

Innovation - Target discovery

MA Lindsay

NATURE REVIEWS DRUG DISCOVERY (2003)

Review Biotechnology & Applied Microbiology

Target selection in drug discovery

J Knowles et al.

NATURE REVIEWS DRUG DISCOVERY (2003)

Article Biochemistry & Molecular Biology

Antitumor effect of G3139 Bcl-2 antisense oligonucleotide is independent of its immune stimulation by CpG motifs in SCID mice

V Wacheck et al.

ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT (2002)

Review Pharmacology & Pharmacy

Fomivirsen

LR Grillone et al.

DRUGS OF TODAY (2001)