4.8 Article

The UCSC Cancer Genomics Browser: update 2013

Journal

NUCLEIC ACIDS RESEARCH
Volume 41, Issue D1, Pages D949-D954

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gks1008

Keywords

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Funding

  1. National Cancer Institute (NCI) [5U24CA143858]
  2. American Association for Cancer Research (AACR) Stand Up To Cancer (SU2C) program [SU2C-AACR-DT0409]
  3. UCSF Helen Diller Family Comprehensive Cancer Center
  4. Howard Hughes Medical Institute
  5. Direct For Biological Sciences [845783] Funding Source: National Science Foundation
  6. Div Of Biological Infrastructure [845783] Funding Source: National Science Foundation

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The UCSC Cancer Genomics Browser (https://genome-cancer.ucsc.edu/) is a set of web-based tools to display, investigate and analyse cancer genomics data and its associated clinical information. The browser provides whole-genome to base-pair level views of several different types of genomics data, including some next-generation sequencing platforms. The ability to view multiple datasets together allows users to make comparisons across different data and cancer types. Biological pathways, collections of genes, genomic or clinical information can be used to sort, aggregate and zoom into a group of samples. We currently display an expanding set of data from various sources, including 201 datasets from 22 TCGA (The Cancer Genome Atlas) cancers as well as data from Cancer Cell Line Encyclopedia and Stand Up To Cancer. New features include a completely redesigned user interface with an interactive tutorial and updated documentation. We have also added data downloads, additional clinical heatmap features, and an updated Tumor Image Browser based on Google Maps. New security features allow authenticated users access to private datasets hosted by several different consortia through the public website.

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