Journal
NUCLEIC ACIDS RESEARCH
Volume 39, Issue -, Pages W283-W287Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkr311
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Funding
- National Institutes of Health [GM030518, GM094597, CA121852]
- National Natural Science Foundation of China [60873040]
- Shanghai Education Development Foundation
- Howard Hughes Medical Institute
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We describe PredUs, an interactive web server for the prediction of protein-protein interfaces. Potential interfacial residues for a query protein are identified by 'mapping' contacts from known interfaces of the query protein's structural neighbors to surface residues of the query. We calculate a score for each residue to be interfacial with a support vector machine. Results can be visualized in a molecular viewer and a number of interactive features allow users to tailor a prediction to a particular hypothesis. The PredUs server is available at: http://wiki.c2b2.columbia.edu/honiglab_public/index.php/Software:PredUs.
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