Journal
NUCLEIC ACIDS RESEARCH
Volume 40, Issue D1, Pages D761-D769Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkr1023
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Funding
- Swiss Federal Government through the Federal Office of Education and Science
- European Union [226073, 222886-2]
- French government through ANR MIRI [BLAN08-1335497]
- Swiss SystemsX.ch initiative
- INRIA-Rhone-Alpes
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UniPathway (http://www.unipathway.org) is a fully manually curated resource for the representation and annotation of metabolic pathways. UniPathway provides explicit representations of enzyme-catalyzed and spontaneous chemical reactions, as well as a hierarchical representation of metabolic pathways. This hierarchy uses linear subpathways as the basic building block for the assembly of larger and more complex pathways, including species-specific pathway variants. All of the pathway data in UniPathway has been extensively cross-linked to existing pathway resources such as KEGG and MetaCyc, as well as sequence resources such as the UniProt KnowledgeBase (UniProtKB), for which UniPathway provides a controlled vocabulary for pathway annotation. We introduce here the basic concepts underlying the UniPathway resource, with the aim of allowing users to fully exploit the information provided by UniPathway.
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