Journal
SYNLETT
Volume 26, Issue 16, Pages 2288-2292Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1381060
Keywords
nitrile; carboxylic acid; diisobutylaluminum hydride; aluminum amide; ammonium chloride
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Funding
- University of Bialystok [BST-124]
- EU as a part Operational Program Development of Eastern Poland [POPW.01.03.00-20-034/09-00]
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A convenient, one-step procedure is presented for the conversion of carboxylic acids or their derivatives (esters, lactones, amides) to nitriles with an aminoalane reagent prepared from diisobutylaluminum hydride (DIBAL-H) and ammonium chloride.
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