Related references
Note: Only part of the references are listed.Expression of Apolipoprotein B in the Kidney Attenuates Renal Lipid Accumulation
Marcin Krzystanek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents
C. A. Stein et al.
NUCLEIC ACIDS RESEARCH (2010)
Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100
Rosie Z. Yu et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Lack of Pharmacokinetic Interaction of Mipomersen Sodium (ISIS 301012), a 2 '-O-Methoxyethyl Modified Antisense Oligonucleotide Targeting Apolipoprotein B-100 Messenger RNA, with Simvastatin and Ezetimibe
Rosie Z. Yu et al.
CLINICAL PHARMACOKINETICS (2009)
Short Antisense Oligonucleotides with Novel 2′-4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals
Punit P. Seth et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Efficient in vivo delivery of siRNA to the liver by conjugation of α-tocopherol
Kazutaka Nishina et al.
MOLECULAR THERAPY (2008)
Antisense apolipoprotein B therapy: where do we stand?
Fatima Akdim et al.
CURRENT OPINION IN LIPIDOLOGY (2007)
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals
Eric E. Swayze et al.
NUCLEIC ACIDS RESEARCH (2007)
Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B
John J. P. Kastelein et al.
CIRCULATION (2006)
The immune response in atherosclerosis: a double-edged sword
Goran K. Hansson et al.
NATURE REVIEWS IMMUNOLOGY (2006)
RNAi-mediated gene silencing in non-human primates
TS Zimmermann et al.
NATURE (2006)
Plasma protein binding of an antisense oligonucleotide targeting human ICAM-1 (ISIS 2302)
Tanya A. Watanabe et al.
OLIGONUCLEOTIDES (2006)
Characterization of modified antisense oligonucleotides in Xenopus laevis embryos
KA Lennox et al.
OLIGONUCLEOTIDES (2006)
On the in vitro and in vivo properties of four locked nucleic acid nucleotides incorporated into an anti-H-Ras antisense oligonucleotide
K Fluiter et al.
CHEMBIOCHEM (2005)
An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis
RM Crooke et al.
JOURNAL OF LIPID RESEARCH (2005)
Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions
M Leblanc et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication
J Elmén et al.
FEBS LETTERS (2004)
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
J Soutschek et al.
NATURE (2004)
A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis
AP Simoes-Wust et al.
OLIGONUCLEOTIDES (2004)
Downregulation of p21((WAF1/CIP1)) and estrogen receptor alpha in MCF-7 cells by antisense oligonucleotides containing locked nucleic acid (LNA)
JS Jepsen et al.
OLIGONUCLEOTIDES (2004)
Reduction of lipocalin-type prostaglandin D synthase in the preoptic area of female mice mimics estradiol effects on arousal and sex behavior
JA Mong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′-O-methyl RNA, phosphorothioates and small interfering RNA
A Grünweller et al.
NUCLEIC ACIDS RESEARCH (2003)
Fatty liver in familial hypobetalipoproteinemia: triglyceride assembly into VLDL particles is affected by the extent of hepatic steatosis
G Schonfeld et al.
JOURNAL OF LIPID RESEARCH (2003)
Nuclease stability of LNA oligonucleotides and LNA-DNA chimeras
M Frieden et al.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2003)
Expanding the design horizon of antisense oligonucleotides with alpha-L-LNA
M Frieden et al.
NUCLEIC ACIDS RESEARCH (2003)
Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design
DA Braasch et al.
NUCLEIC ACIDS RESEARCH (2002)
Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase
AN Elayadi et al.
BIOCHEMISTRY (2002)
Design of antisense oligonucleotides stabilized by locked nucleic acids
J Kurreck et al.
NUCLEIC ACIDS RESEARCH (2002)