Journal
NUCLEIC ACIDS RESEARCH
Volume 39, Issue -, Pages D591-D595Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkq1154
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Funding
- ERA-NET PathoGenoMics
- German Research Foundation (DFG) [DFG RA 1719/1-1]
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Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins ('effectors') crucial for understanding the molecular bacterium-host interactions. Effective (http://effectors.org) is a database of predicted bacterial secreted proteins, implementing two complementary prediction strategies for protein secretion: the identification of eukaryotic-like protein domains and the recognition of signal peptides in amino acid sequences. The Effective web portal provides user-friendly tools for browsing and retrieving comprehensive precalculated predictions for whole bacterial genomes as well as for the interactive prediction of effectors in user-provided protein sequences.
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