4.8 Article

GreenPhylDB v2.0: comparative and functional genomics in plants

Journal

NUCLEIC ACIDS RESEARCH
Volume 39, Issue -, Pages D1095-D1102

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkq811

Keywords

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Funding

  1. CGIAR [G4008.21]
  2. National institutes of Health [R01 GM087218-01]
  3. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM087218] Funding Source: NIH RePORTER

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GreenPhylDB is a database designed for comparative and functional genomics based on complete genomes. Version 2 now contains sixteen full genomes of members of the plantae kingdom, ranging from algae to angiosperms, automatically clustered into gene families. Gene families are manually annotated and then analyzed phylogenetically in order to elucidate orthologous and paralogous relationships. The database offers various lists of gene families including plant, phylum and species specific gene families. For each gene cluster or gene family, easy access to gene composition, protein domains, publications, external links and orthologous gene predictions is provided. Web interfaces have been further developed to improve the navigation through information related to gene families. New analysis tools are also available, such as a gene family ontology browser that facilitates exploration. GreenPhylDB is a component of the South Green Bioinformatics Platform (http://southgreen.cirad.fr/) and is accessible at http://greenphyl.cirad.fr. It enables comparative genomics in a broad taxonomy context to enhance the understanding of evolutionary processes and thus tends to speed up gene discovery.

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