Journal
NUCLEIC ACIDS RESEARCH
Volume 39, Issue -, Pages D124-D128Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkq992
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Funding
- National Institutes of Health [R01 HG003985]
- NATIONAL HUMAN GENOME RESEARCH INSTITUTE [R01HG003985] Funding Source: NIH RePORTER
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The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe > 130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org.
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