Journal
NUCLEIC ACIDS RESEARCH
Volume 37, Issue -, Pages D141-D145Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkn879
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Funding
- Office of Science
- U. S. Department of Energy [DE-FG02-99ER62848, DE-FG02-04ER63933]
- National Science Foundation [DBI-0328255]
- National Institute of Environmental Health Sciences Superfund Basic Research Program [P42ES04911]
- NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [P42ES004911] Funding Source: NIH RePORTER
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The Ribosomal Database Project (RDP) provides researchers with quality-controlled bacterial and archaeal small subunit rRNA alignments and analysis tools. An improved alignment strategy uses the Infernal secondary structure aware aligner to provide a more consistent higher quality alignment and faster processing of user sequences. Substantial new analysis features include a new Pyrosequencing Pipeline that provides tools to support analysis of ultra high-throughput rRNA sequencing data. This pipeline offers a collection of tools that automate the data processing and simplify the computationally intensive analysis of large sequencing libraries. In addition, a new Taxomatic visualization tool allows rapid visualization of taxonomic inconsistencies and suggests corrections, and a new class Assignment Generator provides instructors with a lesson plan and individualized teaching materials. Details about RDP data and analytical functions can be found at http://rdp.cme.msu.edu/.
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