Journal
NUCLEIC ACIDS RESEARCH
Volume 37, Issue 8, Pages 2419-2433Publisher
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkp145
Keywords
-
Categories
Funding
- FCT (Portuguese Science Foundation) [PTDC/EIA/67722/2006, ERAPGFP/06.030A, SFRH/BD/29246/2006]
- ANR [NT05-3_45205]
- INRIA
Ask authors/readers for more resources
The discovery of microRNAs (miRNAs), almost 10 years ago, changed dramatically our perspective on eukaryotic gene expression regulation. However, the broad and important functions of these regulators are only now becoming apparent. The expansion of our catalogue of miRNA genes and the identification of the genes they regulate owe much to the development of sophisticated computational tools that have helped either to focus or interpret experimental assays. In this article, we review the methods for miRNA gene finding and target identification that have been proposed in the last few years. We identify some problems that current approaches have not yet been able to overcome and we offer some perspectives on the next generation of computational methods.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available