Related references
Note: Only part of the references are listed.Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificity
Pinar Iyidogan et al.
BIOCHEMISTRY (2008)
Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs
W. Knecht et al.
GENE THERAPY (2007)
Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities
Monica L. Gerth et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure
Dario Segura-Pena et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2
Monica L. Gerth et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants
N. Solaroli et al.
GENE THERAPY (2007)
Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis
Luke L. Lairson et al.
NATURE CHEMICAL BIOLOGY (2006)
Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells
LP Jordheim et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2006)
Studies of nucleoside transporters using novel autofluorescent nucleoside probes
J Zhang et al.
BIOCHEMISTRY (2006)
DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity
SW Song et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The nucleoside transport proteins, NupC and NupG, from Escherichia coli: specific structural motifs necessary for the binding of ligands
SG Patching et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2005)
Nucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolution
KM Muller et al.
NUCLEIC ACIDS RESEARCH (2005)
Pyrrolo-dC and pyrrolo-C:: fluorescent analogs of cytidine and 2′-deoxycytidine for the study of oligonucleotides
DA Berry et al.
TETRAHEDRON LETTERS (2004)
Structures of thymidine kinase 1 of human and mycoplasmic origin
M Welin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: Studies of the Drosophila deoxyribonucleoside kinase
NE Mikkelsen et al.
BIOCHEMISTRY (2003)
Characterization of Herpes Simplex Virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity
MS Kokoris et al.
PROTEIN SCIENCE (2002)
Structure and function of cellular deoxyribonucleoside kinases
S Eriksson et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2002)
A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines
W Knecht et al.
EMBO JOURNAL (2002)
Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase
XY Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Function-based isolation of novel enzymes from a large library
MJ Olsen et al.
NATURE BIOTECHNOLOGY (2000)
Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster
W Knecht et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants
B Munch-Petersen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
