4.8 Article

INTERFEROME: the database of interferon regulated genes

Journal

NUCLEIC ACIDS RESEARCH
Volume 37, Issue -, Pages D852-D857

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkn732

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Funding

  1. National Health and Medical Research Council, Australia
  2. CRC for chronic inflammatory disease

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INTERFEROME is an open access database of types I, II and III Interferon regulated genes (http://www.interferome.org) collected from analysing expression data sets of cells treated with IFNs. This database of interferon regulated genes integrates information from high-throughput experiments with annotation, ontology, orthologue sequences from 37 species, tissue expression patterns and gene regulatory information to enable a detailed investigation of the molecular mechanisms underlying IFN biology. INTERFEROME fulfils a need in infection, immunity, development and cancer research by providing computational tools to assist in identifying interferon signatures in gene lists generated by high-throughput expression technologies, and their potential molecular and biological consequences.

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