Journal
NUCLEAR MEDICINE AND BIOLOGY
Volume 40, Issue 3, Pages 314-320Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nucmedbio.2012.12.010
Keywords
Specific activity; Carbon-11; Fluorine-18
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Specific Activity (SA), defined as the amount of radioactivity per unit mass of a compound is arguably one of the most important parameters in radiopharmaceutical development, particularly in quality control of carbon-11 and fluorine-18 labeled compounds. This review article will outline the progression of improvements in SA over the last few decades. The International Symposium of Radiopharmaceutical Chemistry (ISRC/ISRS) abstracts were an excellent source of materials for this review and will be referenced throughout. (C) 2013 Elsevier Inc. All rights reserved.
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