Journal
NUCLEAR MEDICINE AND BIOLOGY
Volume 39, Issue 5, Pages 601-608Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nucmedbio.2011.11.005
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Specific activity (SA), defined as the amount of radioactivity per unit mass of a compound, is arguably one of the most important parameters in radiopharmaceutical development, particularly in quality control of carbon-11- and fluorine-18-labeled compounds. This review article will outline the progression of improvements in SA over the last few decades. The International Symposium of Radiopharmaceutical Chemistry abstracts were an excellent source of materials for this review and will be referenced throughout. (C) 2012 Elsevier Inc. All rights reserved.
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