Journal
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
Volume 649, Issue 1, Pages 222-224Publisher
ELSEVIER
DOI: 10.1016/j.nima.2010.12.024
Keywords
Biofilm; Mass spectrometry; Postionization; Synchrotron radiation; Extreme ultraviolet; Vacuum ultraviolet
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Funding
- NIBIB NIH HHS [R01 EB006532-04, R01 EB006532] Funding Source: Medline
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Vacuum and extreme ultraviolet radiation from 8 to 24 eV generated at a synchrotron was used to postionize laser desorbed neutrals of antibiotic-treated biofilms and a modified fullerene using laser desorption postionization mass spectrometry (LDPI-MS). Results show detection of the parent ion, various fragments, and extracellular material from biofilms using LDPI-MS with both vacuum and extreme ultraviolet photons. Parent ions were observed for both cases, but extreme ultraviolet photons (16-24 eV) induced more fragmentation than vacuum ultraviolet (8-14 eV) photons. (C) 2010 Elsevier B.V. All rights reserved.
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