Journal
ARCHIVES OF CARDIOVASCULAR DISEASES
Volume 108, Issue 12, Pages 617-625Publisher
ELSEVIER MASSON
DOI: 10.1016/j.acvd.2015.06.007
Keywords
Heart failure; Cardiac resynchronization; Electromechanical clyssynchrony
Categories
Ask authors/readers for more resources
Background. - The relationship between electrical and mechanical indices of cardiac dyssynchronization in systolic heart failure (HF) remains poorly understood. Objectives. - We examined retrospectively this relationship by using the daily practice tools in cardiology in recipients of cardiac resynchronization therapy (CRT) systems. Methods. - We studied 119 consecutive patients in sinus rhythm and QRS >= 120 ms (mean: 160 +/- 17 ms) undergoing CRT device implantation. P wave duration, PR, ePR (end of P wave to QRS onset), QT, RR-QT, JT and QRS axis and morphology were putative predictors of atrioventricular (diastolic filling time [DFT]/RR), interventricular mechanical dyssynchrony (IVMD) and left intraventricular mechanical dyssynchrony (left ventricular pre-ejection interval [PEI] and other measures) assessed by transthoracic echocardiography (TIE). Correlations between TIE and electrocardiographic measurements were examined by linear regression. Results. - Statistically significant but relatively weak correlations were found between heart rate (r = -0.5), JT (r = 0.3), QT (r = 0.3), RR-QT intervals (r = 0.5) and DFT/RR, though not with PR and QRS intervals. Weak correlations were found between: (a) QRS (r = 0.3) and QT interval (r = 0.3) and (b) IVMD > 40 ms; and between (a) ePR (r = -0.2), QRS (r = 0.4), QT interval (r = 0.3) and (b) LVPEI, though not with other indices of intraventricular dyssynchrony. Conclusions. - The correlations between electrical and the evaluated mechanical indices of cardiac dyssynchrony were generally weak in heart failure candidates for CRT. These data may help to explain the discordance between electrocardiographic and echocardiographic criteria of ventricular dyssynchrony in predicting the effect of CRT. (C) 2015 Published by Elsevier Masson SAS.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available