Journal
NEW PHYTOLOGIST
Volume 199, Issue 3, Pages 639-649Publisher
WILEY
DOI: 10.1111/nph.12291
Keywords
AP2; development; ethylene-responsive factors; regulation of transcription; stress response; transcription factors
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Transcription factors belonging to the APETALA2/Ethylene Responsive Factor (AP2/ERF) family are conservatively widespread in the plant kingdom. These regulatory proteins are involved in the control of primary and secondary metabolism, growth and developmental programs, as well as responses to environmental stimuli. Due to their plasticity and to the specificity of individual members of this family, AP2/ERF transcription factors represent valuable targets for genetic engineering and breeding of crops. In this review, we integrate the evidence collected from functional and structural studies to describe their different mechanisms of action and the regulatory pathways that affect their activity.
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