Journal
NEW JOURNAL OF CHEMISTRY
Volume 38, Issue 1, Pages 302-307Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3nj01149f
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Funding
- UGC, New Delhi
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An efficient one pot multi-component sequential reaction of phenyl hydrazine, malanonitrile and a diverse range of aldehydes to afford highly functionalised pyrazoles is reported. The reaction proceeds in water using molecular iodine as a catalyst, with no by-product formation, and involves simple operation requiring no column chromatography. Thus, this protocol fulfils all of the criteria that define green chemistry.
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