Journal
NEW JOURNAL OF CHEMISTRY
Volume 38, Issue 7, Pages 2941-2945Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nj00018h
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Funding
- National Natural Science Foundation of China [21244007]
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A novel ratiometric fluorescent probe based on hydroxylnaphthalene 2-cyanoacrylate was developed to act as a luminescent probe for biological fluoride ion detection. The probe is responsive and highly selective for fluoride ions over other common anions; it also exhibits a very low detection limit of 8.54 mu M. The deprotonation of the phenol moieties leads to a fluorescent change in the probe. The biological applications of the probe were also evaluated and it was found to exhibit a low cytotoxicity, a good water solubility and membrane permeability. The probe was, therefore, employed as a sensing probe for the detection of fluoride ions in living cells.
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