Journal
NEW JOURNAL OF CHEMISTRY
Volume 38, Issue 11, Pages 5181-5185Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nj00724g
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Funding
- Deutsche Forschungsgemeinschaft [AR 783/1-1, SFB 765]
- Federal Ministry of Education and Research [BMBF INUNA 0312027]
- Humboldt University Gender Equal Opportunities Fund [52516/0105]
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Mimicking cellular processes by functional comparable structures helps to understand their molecular mechanism. We report on an oligonucleotide modified with two alpha-tocopherol anchors mimicking tetherin, a cellular protein reducing spreading of viruses. The lipophilic DNA was incorporated into vesicles and virus like particles; their aggregation was induced by the complement addition.
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