Journal
NEW JOURNAL OF CHEMISTRY
Volume 37, Issue 3, Pages 624-631Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2nj41021d
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21272115]
- Natural Science Foundation of Jiangsu Province [BK2009384]
- Fundamental Research Funds for the Central Universities [NUST2011ZDJH19]
Ask authors/readers for more resources
In the presence of the [Cp*IrCl2](2)/NaOH system, the direct N-alkylation of 2-aminoquinazolines and 2-aminopyrimidines with alcohols afforded the N-exosubstituted 2-(N-alkylamino)quinazolines and 2-(N-alkylamino)pyrimidines with 71-96% yields and complete regioselectivities. The protocol is highly attractive because of easily available starting materials, high atom efficiency and environmental friendliness.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available