4.6 Article

Water-soluble dendritic polyaspartic porphyrins: potential photosensitizers for photodynamic therapy

Journal

NEW JOURNAL OF CHEMISTRY
Volume 36, Issue 1, Pages 28-31

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1nj20733d

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Funding

  1. Chinese Ministry of Education [210015]
  2. National Natural Science Foundation of China [20804012]
  3. Natural Science Foundation of Hebei Province [B2009000169]
  4. Department of Education of Hebei Province [2007413]
  5. Natural Science Foundation of Hebei University [2007105]

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We prepared these photosensitizers with two-block structures: porphyrin cores for singlet oxygen generation and branched dendritic polyaspartic as hydrophilic shells for inducing water solubility, thus reducing cytotoxicity and giving high singlet oxygen yields.

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