Journal
NEW JOURNAL OF CHEMISTRY
Volume 36, Issue 7, Pages 1519-1526Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2nj40128b
Keywords
-
Categories
Funding
- Isidro Parga Pondal Program (Xunta de Galicia, Spain)
- Spanish Ministerio de Ciencia y Tecnologia [CTQ2011-22436]
- Xunta de Galicia [PGIDIT07-PXIB209041PR, PGIDIT10-PXIB209113PR, 2007/085]
Ask authors/readers for more resources
Nucleophilic aromatic substitution for nitro-activated substrates in the presence of glymes and crown ethers is reported. The kinetic study reveals the many-sided nature of the polyether-catalyzed SNAr mechanism as well as the main features affecting the course of the reaction. Thus, the process can be efficiently controlled by the catalyst through a molecular-recognition process, being also strongly dependent on the electronic structure of the substrate and, therefore, giving rise to a versatile reaction system. The kinetic model proposed herein allows quantifying the fractions of reaction proceeding through the different routes. Information on the nature of the host-guest interaction between the catalyst and the substrate will also be extracted.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available