A novel reaction-based, chromogenic and turn-on'' fluorescent chemodosimeter for fluoride detection

A reactivity based fluoride sensing method exploiting both its nucleophilic and basic character has been developed. This novel dual mode strategy offers both a visible naked-eye'' and a fluorescence-on'' detection. Upon nucleophilic addition of F(-) to fluorochromic maleimides this approach allows for selective detection of fluoride from other (critical) basic anions, such as acetate, hydroxide or cyanide.